Friday, July 22, 2005

Vaginal Emergency Contraceptives

A study was released in the current issue of Fertility & Sterility that compares emergency contraceptives taken orally versus vaginally. The authors concluded that "vaginal route of administration of emergency contraception regimens may be as efficacious as the oral route." The abstract is available here, and MedlinePlus has a summary here.

The rationale for trying this is, in part, to reduce the nausea and vomiting many women experience when using emergency contraception. Notably, though, the study only involved 9 subjects, so more research would likely need to be done with a bigger study group. Oddly, women in the study "were asked to sit for four hours and restrict their physical activity for another four hours" after inserting the hormones. This seems like an inconvenience that could make oral medicines a better choice for some women.
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Anonymous Anonymous said...

If the provider who dispenses the ECP has any compassion (or decency) towards the patient, they'll be sure to give the patient some benadryl or at least suggest taking it with the ECP. Benadryl has known anti-emetic (no nausea/vomiting) properties and is commonly give alongside ECP by educated providers. Sorry for the long, awkward sentence. You've got a terrific web-page, Rachel--keep up the good work! julie

3:24 PM  
Blogger Rachel said...

Thanks, Julie. I hadn't heard of this previously. In fact, I never knew Benadryl had anti-emetic properties, because it knocks me out in about 20 minutes. :) I poked around online and found several sites recommending this, though. I double-checked the drug databases and didn't find any interactions listed for the two. Thanks for the tip!

8:05 AM  

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